Biocontainment Facility Operations and Maintenance Support

LRRI has 50 years of experience performing research with high-risk agents and compounds requiring the use of containment laboratories and animal housing facilities.


LRRI operates 500,000 sq. ft. of research facilities including 50,000 sq. ft of containment space for chemical, radiological, and biological materials. This includes 20,000 sq. ft. of levels 2 and 3 biocontainment safety laboratories. LRRI is experienced, licensed, and certified by regulating agencies such as the U.S. Department of Agriculture (USDA), U.S. Centers for Disease Control and Prevention (CDC), and U.S. Food and Drug Administration (FDA).

LRRI provides expert assistance to designers, contractors, commissioning agents, and owners in the development and operation of biocontainment facilities. LRRI brings the practical experience and lessons learned from an owner/operator perspective to achieve operational readiness and reduce performance risk in minimal time.


  • Requirements Development
  • Design Review
  • Regulatory Compliance Assessment
  • Construction Phase Support
  • Commissioning and Validation Support
  • O&M Support, including:
    • Procedure Compliance Review
    • Procedures Development and Implementation
    • Facility Documentation
    • Personnel Training
    • Operating Cost Assessment
  • Research Animal Management


  • Biosafety
  • Facility Access Control
  • Facility Entry and Exit
  • PPE Use
  • Decontamination/Sterilization
  • Waste Management
  • Maintenance
  • Animal Husbandry
  • Bioagent Security
  • Incident Response
  • Emergency Management
  • Facility Shutdown and Restart
  • Certification and Inspections