Basic & Translational Research on COPD


 

Studies are ongoing that show the role of Bcl-2 family of proteins in sustaining mucous cell metaplasia in chronic diseases.  These studies are determining how the Bcl-2 family of proteins regulate pulmonary inflammation.

Ongoing studies focus on understanding how gene variations in genes encoding the Bcl-2 family of proteins or those that regulate expression of these genes, may be affecting the mucus regulatory network.